Expanding Simulated Moving Bed Chromatography into Ternary Separations in Analogy to Dividing Wall Column Distillation
نویسندگان
چکیده
منابع مشابه
Optimization of azeotropic protein separations in gradient and isocratic ion-exchange simulated moving bed chromatography.
The separation of dilute binary mixtures of proteins by salt aided ion-exchange simulated moving bed (SMB) chromatography is optimized with respect to throughput, desorbent consumption and salt consumption. The optimal flow-rate ratios are analytically determined via an adopted "triangle theory". Azeotropic phenomena are included in this procedure. The salt concentrations in the feed and recycl...
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The simulated moving bed (SMB) process has been extensively used in industrial separations for binary and pseudo-binary separations. In pseudo-binary mixtures because the desired component is the most or least retained, the other components do not have to be separated. The UOP Parex process for p-xylene purification is an example. When non-target components have similar adsorption behaviors, th...
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The salt-gradient operation mode used in ion-exchange simulated moving bed chromatography (SMBC) can improve the efficiency of protein separations. A detailed model that takes into account any kind of adsorption/ion-exchange equilibrium, salt gradient, size exclusion, mass transfer resistance, and port periodic switching mechanism, was developed to simulate the complex dynamics. The model predi...
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Simulated moving bed (SMB) chromatography has been widely studied in past and there have been various operating schemes proposed for efficient separation of binary mixtures. SMB is a promising option of separation because of its capability to achieve efficient separation even when the components differ very little in terms of affinity towards the stationary phase. However, separation of a terna...
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The aim of this work is to implement heterogeneous azeotropic distillation schemes in a dividing wall column (DWC) for a feed mixture of water (W), acetic acid (HAC) and an organic component (X). The original design makes use of X to act as an entrainer to facilitate the separation of water and HAC, and we also propose a DWC design based on this idea. This DWC design reduces the capital cost, b...
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ژورنال
عنوان ژورنال: Industrial & Engineering Chemistry Research
سال: 2020
ISSN: 0888-5885,1520-5045
DOI: 10.1021/acs.iecr.0c00572